Non-invasive assessment of visual system structure and function in animal models
Presenters
Holly Chinnery, PhD, University Melbourne; Carol B. Toris, PhD, University of Nebraska;
Mathias W. Seeliger, MD, FARVO, University of Tübingen; Ben Sajdak, PhD, University of Wisconsin-Oshkosh; Nimesh Patel, PhD, University of Houston
Mathias W. Seeliger, MD, FARVO, University of Tübingen; Ben Sajdak, PhD, University of Wisconsin-Oshkosh; Nimesh Patel, PhD, University of Houston
Description
Audience: Vision scientists who work with research animals.
Summary: The use of animal models is vital in vision research, including the better understanding of disease mechanisms as well as the development and pre-clinical testing of novel therapies. Major advances have been made in recent years in technologies that allow the non-invasive functional and morphological assessment of the visual system, including the eye and the central visual pathways. While clinical applications in human subjects may be the primary intended use of many of these technologies, they have also been adapted for application in small and large animal models. These technologies enhance efficiency in animal studies, by reducing the number of animals needed, and thereby address the tenets of the three Rs: replace, reduce and refine. In this Workshop, which is organized by the ARVO Animals in Research Committee, the audience will be updated on the application and translational aspects of non-invasive, state-of-the-art technologies for functional and morphological assessment, including high-resolution imaging methods, measurement of aqueous humor dynamics, and functional assessment of the retina and central visual pathways.
Summary: The use of animal models is vital in vision research, including the better understanding of disease mechanisms as well as the development and pre-clinical testing of novel therapies. Major advances have been made in recent years in technologies that allow the non-invasive functional and morphological assessment of the visual system, including the eye and the central visual pathways. While clinical applications in human subjects may be the primary intended use of many of these technologies, they have also been adapted for application in small and large animal models. These technologies enhance efficiency in animal studies, by reducing the number of animals needed, and thereby address the tenets of the three Rs: replace, reduce and refine. In this Workshop, which is organized by the ARVO Animals in Research Committee, the audience will be updated on the application and translational aspects of non-invasive, state-of-the-art technologies for functional and morphological assessment, including high-resolution imaging methods, measurement of aqueous humor dynamics, and functional assessment of the retina and central visual pathways.
Estimated Duration
1 hour 30 minutes
Members-in-Training ($0); Members ($0)
Description
Organizers
Neena B. Haider, PhD, Harvard Medical School; Christophe P. Ribelayga, MS, PhD, University of Houston College of Optometry; Ifat Sher, PhD, Sheba Medical Center Goldschleger Eye Institute; Amy Lo, PhD, The University of Hong Kong Department of Ophthalmology.
Neena B. Haider, PhD, Harvard Medical School; Christophe P. Ribelayga, MS, PhD, University of Houston College of Optometry; Ifat Sher, PhD, Sheba Medical Center Goldschleger Eye Institute; Amy Lo, PhD, The University of Hong Kong Department of Ophthalmology.
This webinar is hosted by ARVO's Animals in Research Committee.
Attendees will leave this session with the ability to:
Learning objectives
- Cite major advances in technologies that allow the non-invasive functional and morphological assessment of the visual system.
- Plan their animal studies more efficiently.
- Include and optimize the use of non-invasive state-of-the art technologies for functional and morphological assessment of the visual system.
*This webinar was hosted live on July 19, 2023.
