""Session 5: Power and Sample Size Calculation for non-inferiority trial, by Dr. Xiangrong Kong"
This lecture will cover power and sample size calculation for non-inferiorty trial. By working through a real-world example of the design of an AMD trial, we will introduce the concept, the statistical hypotheses, and key parameters related to non-inferiorty trial. We will illustrate the process of translating clinical knowledge and interest into specification of key parameters needed for the PSS calculation. The calculation will be demonstrated using sample size software such as PASS and Stata.